site stats

Irf1 molecular weight

WebJun 19, 2024 · This observation was further corroborated by molecular studies showing increased percentages of IL-17A/IFN-γ-producing CD4 + T cells in the central nervous …

Anti IRF1 Antibody (PrecisionAb Polyclonal Antibody) Bio-Rad

WebMolecular function Cellular component: Biological process ... Interferon regulatory factor 1 is a protein that in humans is encoded by the IRF1 gene. ... Body weight: Normal Anxiety: Normal Neurological assessment: Normal Grip strength: Normal Hot plate: Normal Dysmorphology: WebApr 16, 2002 · Molecular Function: RNA polymerase II transcription regulatory region sequence-specific DNA binding Source:ARUK-UCL. 1 publication. ... Note: MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88-associated IRF1. By similarity Keywords. Cellular component. #Cytoplasm; #Nucleus ... gas oven slow to heat https://lixingprint.com

PANoptosis: An inflammatory programmed cell death pathway

WebJan 15, 2024 · Molecular and functional characterization of interferon regulatory factor 1 (IRF1) ... 10 μg/g body weight] for 3 h, whose spleen and kidney were used for the extraction of total RNA by using Trizol Reagent (Invitrogen). The first-strand cDNA was synthesized from above total RNA and served as template to amplify ORF sequence of Xt-IRF1 by PCR ... WebDec 1, 2024 · LcIRF2, LcIRF5, LcIRF6, LcIRF10, and LcIRF11 have ORF of 954, 1476, 1473, 1206, and 792 bp, encoding 318, 492, 491, 402, and 264 aa, with a predicted molecular … WebMar 29, 2024 · IRF1 and IRF2 also appear to be important in regulating DC subset development— Irf −/− mice show a loss of splenic and epidermal DCs (due to augmented type I IFN signaling) ( 109, 110) whereas Irf1−/− exhibit an increase in pDCs and a decrease in CD8 + DCs in mice, along with an increase of IL-10 and TGF-β ( 111 ). david gortler washington examiner

IRF1 Gene - GeneCards IRF1 Protein IRF1 Antibody

Category:Molecular characterization and association analysis of porcine ...

Tags:Irf1 molecular weight

Irf1 molecular weight

IRF1 - phosphosite.org

WebJun 30, 2016 · Besides CCL2, the transcription factor IRF1, which has proapoptotic activities was significantly upregulated after IL6/sgp80 or OSM stimulation. qRT-PCR revealed a rapid (within 2 hours) and strong (10- to 12-fold) induction of IRF1 mRNA after OSM or IL6/sgp80 stimulation in HeLa and SW756 cells (Fig. 6A; P <0.0001). WebIRF1 Protein Molecular Weight & PI . The parameters have been computed for the following feature . FT CHAIN 1-325 Interferon regulatory factor 1. Molecular weight (Da) 36502.21 Theoretical pI . 5.22 Bulk Order of Recombinant IRF1 Protein . Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the ...

Irf1 molecular weight

Did you know?

WebApr 4, 2024 · IRF-1 is an important signaling protein in the interferon pathway. It not only activates gene expression as a transcription factor, but may perpetuate disease by leading to a dysregulated epigenome. Data suggest that interferon regulatory factors 1 and 2 (IRF1 and IRF2) may serve as potential targets of therapy. WebMay 5, 2014 · Cellular & Molecular Immunology - K63-linked polyubiquitination of IRF1: an essential step in the IL-1 signaling cascade ... Adding weight to this was the observation that SKI-1, ...

WebSep 29, 2024 · Given that IRF-1 is well known to molecularly act downstream of IFN-γ signaling, we also subjected mice lacking IFN-γ to C. rodentium infection. However, compared to control mice, we observed no... WebIRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta …

WebWhen using primary antibodies produced in mouse to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Rabbit Anti-Mouse IgG (Light Chain … WebSep 19, 2010 · Blast analysis revealed that the porcine IRF1 gene has 85.7, 74.3 and 72.9% nucleotide identity with the corresponding human, mouse and rat IRF1 sequences, …

WebIRF1 (Interferon Regulatory Factor 1 (IRF1)) Alternative Name ... Molecular Weight 58.1 kDa UniProt P15314 Pathways Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive ...

WebDec 1, 2024 · The predicted molecular weight of the Cf IRF1 protein was approximately 40 kDa. Using the SMART program and NCBI conserved domain search program, the N-terminus of the Cf IRF1 protein was predicted to encode an IRF1 domain, similar to IRF1 family proteins of other species ( Fig. 2 A ). Download : Download high-res image (2MB) gas ovens repairsWebMay 5, 2014 · Interleukin 1 (IL-1) is a pleiotropic cytokine that regulates immune and inflammatory responses by inducing the expression of a variety of pro-inflammatory cytokines and chemokines. gas oven south africaWebJan 15, 2024 · Interferon regulatory factor 1 (IRF1) is an important regulator in controlling the transcription of type I interferon genes, and its functions have been well-characterized in mammals, birds and fish. However, little information is available regarding the function of amphibian IRF1. gas ovens south africaWebJul 8, 2024 · IRF1 expression is associated with the expression of IFNβ, which leads to the activation of the JAK-STAT pathway. Blocking the JAK-STAT pathway with the Janus kinase inhibitor (JAKinib)... david gothelf hendersonWebJan 15, 2024 · IRF1 are marked using red, and HSPA4, PDLIM4, and VDAC1 are illustrated in dark, common and light yellow, respectively; TCF7, SKP1, and PPP2CA appear as dark, … gas oven stays on preheatWebIRF1-regulated gene expression equipped low-grade PDAC cells with distinctive properties related to antigen presentation and processing as well as responsiveness to IFN stimulation. david go term analysisWebJul 8, 2024 · IRF1 expression is associated with the expression of IFNβ, which leads to the activation of the JAK-STAT pathway. ... Consistently, molecular function enrichment … gas ovens repair services