WebExogenous galectin-1 or −3 was loaded onto these cells by incubation with the soluble protein. Galectin binding with cells was verified using the corresponding antibodies. ... or four galectin CRDs. 12,48 The only chimeric galectin described so far, is the galectin-related protein (GREP), identified in the freshwater snail Biomphalaria ... WebNov 26, 2024 · Key proteins transferred by epididymal extracellular vesicles (EVs) to the transiting sperm cells contribute to their centrosomal maturation and developmental potential. Although not reported in sperm cells yet, galectin-3-binding protein (LGALS3BP) is known to regulate centrosomal functions in somatic cells. Using the domestic cat …
Galectins and galectin-mediated autophagy regulation: new …
WebFeb 22, 2024 · Cellular functions of galectin. As a soluble protein, galectin plays key regulatory roles both inside and outside of the cell. Intracellular galectins exhibit cellular functions such as regulation of cell growth and apoptosis in a carbohydrate-independent manner and modulate intracellular signaling pathways through protein–protein … parker insurance idaho falls
Galectins at a glance - The Company of Biologists
WebGalectins are a family of carbohydrate-binding proteins with an affinity for beta-galactosides. Galectin-1 (Gal-1) is differentially expressed by various normal and pathological tissues and appears to be functionally polyvalent, with a wide range of biological activity. The intracellular and extrace … WebNot only protein-protein but also protein-carbohydrate interactions are of high relevance for signal transduction in biological systems. Here, we aim to identify novel interacting binding partners for the β-galactoside-binding proteins galectin-1 (Gal-1) and galectin-3 (Gal-3) relevant in the context of the eye disease proliferative ... WebOct 1, 2016 · When applying this concept to the adhesion/growth-regulatory galectins, to bring the status of knowledge for the galectin-related protein (GRP), an integral part of the phylogeny of this class of lectins , , to the same level as already attained for canonical proteins was an obvious necessity. time warner laredo