Atf2 myeloid
WebSep 21, 2024 · Acute myelogenous leukemia (AML) is a cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. The word "acute" in acute myelogenous leukemia denotes the disease's rapid progression. It's called myelogenous (my-uh-LOHJ-uh-nus) leukemia because it affects a group of white blood … WebApr 4, 2024 · basic leucine zipper transcriptional factor ATF-like 2, B-ATF-2, basic leucine zipper transcription factor, ATF-like 2, suppressor of AP-1 regulated by IFN. ... Gain- and loss-of-function studies uncovered a role for Batf2 in myeloid differentiation in both murine and human systems. We thus demonstrate that chronic infection can deplete HSPCs ...
Atf2 myeloid
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WebOct 15, 2009 · Request PDF JNK1/c-Jun and p38α MAPK/ATF-2 pathways are responsible for upregulation of Fas/FasL in human chronic myeloid leukemia K562 cells upon exposure to Taiwan cobra phospholipase A 2 ... http://www.cancer-genetics.org/ATF2.htm
WebATF2 is part of cluster 44 Non-specific - Transcription with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore reflects how strongly associated it is to the cluster. WebIn this study, we show two novel points that ATF2 is re-quired for the induction of granulocytic differentiation and associates with granulocyte-specific transcription factor …
WebJun 15, 2012 · The ATF2 gene is located on chromosome 2q32 and encodes a 505-amino-acid protein, which is ubiquitously expressed, with more abundant expression in the brain (Kara et al., 1990; Takeda et al., 1991).Although the existence of numerous truncated ATF2 isoforms is predicted on the basis of splice variation (), only full-length ATF2 has been … WebDive into the research topics of 'JNK1/c-Jun and p38α MAPK/ATF-2 pathways are responsible for upregulation of Fas/FasL in human chronic myeloid leukemia K562 cells …
WebATF2 is part of cluster 44 Non-specific - Transcription with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore …
WebApr 14, 2024 · Progress in acute myeloid leukaemia treatment is occurring at an unprecedented pace. The past decade has witnessed an increasingly improved scientific … huxley would approveWebMay 1, 2024 · 1. Activating transcription factor 2 (ATF2) Activating transcription factor 2 (ATF2)—also known as cyclic AMP (cAMP) response element (CRE) binding protein 2 (CREB2) and CRE-BP1—is a member of the activating protein-1 (AP1) transcription factor family that regulates gene expression through homo-dimerization or hetero-dimerization … huxley wilberforce debateWebJan 27, 2024 · In contrast, myeloid colony formation was significantly enhanced on administration of CCL5 (Figures 7D and S7I). These findings reveal that CCL5 treatment is sufficient to rescue the myeloid differentiation in Batf2 KO mice. Collectively, the results suggest that BATF2 promotes myeloid differentiation through activation of CCL5. huxley wilberforceWebMar 21, 2024 · BATF2 (Basic Leucine Zipper ATF-Like Transcription Factor 2) is a Protein Coding gene. Diseases associated with BATF2 include Hepatocellular Carcinoma . Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding . An important paralog of this gene is … mary\\u0027s nest chicken bone brothWebApr 15, 2010 · Cooperation among transcription factors is central for their ability to execute specific transcriptional programmes. This Perspective summarizes the emerging role of the transcription factor ATF2 ... mary\u0027s nest chicken bone broth youtubeWebDiscover Atf2's significant phenotypes, expression, images, histopathology and more. Data for gene Atf2 is all freely available for download. Cite IMPC; Help; ... Aplastic anemia, Myeloid leukemia, Myelodys... OMIM:614172: Bleeding Disorder, Platelet-Type, 16: Impaired platelet aggregation, Macrothrombocytopenia, Giant platelets, Platelet ... mary\u0027s nest chicken bone brothWebAtf2(Δ8,9)-driven tumors show enhanced pigmentation, immune infiltration, and metastatic propensity. Similar to mouse Atf2(Δ8,9), we have identified a transcriptionally inactive human ATF2 splice variant 5 (ATF2(SV5)) that enhances the growth and migration capacity of cultured melanoma cells and immortalized melanocytes. mary\\u0027s nest coffee creamer